
Utilization of Fetal Hemoglobin Parameters in Predicting Clinical Severity of Sickle Cell Disease: Retrospective Study ...
Introduction Sickle cell disease (SCD) results from a mutation in codon 6 of the β-globin gene, replacing Adenine (A) with Thymine (T) and causing the substitution of glutamic acid by valine amino acid. This leads to the formation of abnormal hemoglobin S …